Synthesis of new pterocarpans and rapid O-alkylation under microwave irradiation

✍ Scribed by E. A. Evangelista; M. R. C. Couri; D. S. Raslan; R. B. Alves

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 605 KB
• Volume: 17
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20175

✦ Synopsis

Abstract

Herein, it is described five new pterocarpans. Pterocarpans 8 and 9 were synthesized by classical [3 + 2] cycloaddition reaction of 2H‐chromene 7a and 7b with 2‐methoxy‐1,4‐benzoquinone. Pterocarpan 8 was O‐alkylated in the absence of solvents using a domestic microwave oven as a heat source and a classical O‐alkylation method with traditional heating. In this way three more new pterocarpans were obtained. © 2006 Wiley Periodicals, Inc. Heteroatom Chem 17:239–244, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20175