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Synthesis of new mono and dihalo 6-amino-5, 6-dihydro-4H-cyclopenta[b]thiophen-4-ones

✍ Scribed by O. RENAULT; P. DALLEMAGNE; S. RAULT


Book ID
118110715
Publisher
Pharmaceutical Press
Year
1998
Tongue
English
Weight
428 KB
Volume
4
Category
Article
ISSN
2042-7158

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## Abstract magnified image Reactions of 3‐chlorobenzo[__b__]thiophene‐2‐carbonyl chloride with 2‐alkyl‐2‐aminopropanamides have been used to prepare a series of carboxamides **1a‐d** (yields 61‐85%). The products were submitted to base‐catalysed ring closure reactions to give the corresponding 4,