โ Scribed by Wilhelm T. S. Huck; Frank C. J. M. van Veggel; David N. Reinhoudt
No coin nor oath required. For personal study only.
The [3 + 3] macrocyclic compounds 2aโ2c were easily prepared by cyclization of the dialdehyde 8 with the appropiate diamines in refluxing CH~3~CN/MeOH (1/1), in the presence of Ba^2+^ as a template ion. These macrocycles contain three salen units and are therefore, in combination with the crown ether interior, potentially tetranucleating. The length of the diamine bridge and the temperature at which the reaction is carried out, appear to influence the size of the macrocycle formed. In this way, the [4 + 4] macrocycle 2d could be formed selectively over the [3 + 3] macrocycles by carrying out the reaction at room temperature.
๐ SIMILAR VOLUMES
Benzoylacetic acid (1 tool) interacts with ethylenediamine or with propanediamine (2 tool) to yield new N 4 macrocycles 1,5,8,12-tetraazacyclotetradeca-2,4,9,11-tetraphenyl-3,10-dicarboxylic-4,11-diacetic acid-1,8-diene (L~) and 1,5,9,13-tetraazacyclohexadeca-2,4,10,12-tetraphenyl-3,11-dicarboxylic-