Synthesis of new indoyl-1,3,4-oxadiazole and oxadiazine derivatives. Potential monoamine oxidase inhibitor activity

✍ Scribed by Silvia Pérez; Berta Lasheras; Carmen Oset; Antonio Monge

• Publisher: Journal of Heterocyclic Chemistry
• Year: 1997
• Tongue: English
• Weight: 476 KB
• Volume: 34
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570340523

✦ Synopsis

Abstract

New indolyl‐1,3,4‐oxadiazole and oxadiazine derivatives were prepared as reversible monoamine oxidase inhibitors. The compound 5‐(3‐methylindolyl)‐1,3,4‐oxadiazol‐2(3__H__)one was shown to be a good monoamine oxidase B inhibitor.