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Synthesis of New Esters and Oximes with 4-Aminobicyclo[2.2.2]octane Structure and Evaluation of Their Antitrypanosomal and Antiplasmodial Activities.

โœ Scribed by W. Seebacher; C. Schlapper; R. Brun; M. Kaiser; R. Saf; R. Weis


Publisher
John Wiley and Sons
Year
2007
Weight
17 KB
Volume
38
Category
Article
ISSN
0931-7597

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The three dihydronaphtho[l,2,4]trioxines e l l have been synthesized and two of them converted to the five carbamate and ester derivatives 12-16 (Schemes I and 2). The resulting new trioxanes together with two already known and ascaridole (7) were tested for antimalarial activity against the sensiti