Synthesis of new derivatives of β-carboline-hydantoin
✍ Scribed by Miguel F. Braña; Mercedes Garrido; María L. López Rodriguez; Pilar Miguel; M. José Morcillo; A. Riaño
- Book ID
- 112129585
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1990
- Tongue
- English
- Weight
- 267 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-152X
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## Abstract A new and convenient method for the synthesis of pharmacologically interesting compounds containing the tetrahydro‐β‐carboline‐hydantoin moiety linked to a basic chain, together with a structural study, are reported.
The parallel synthesis of new fused tetra, penta and hexacyclic b-carbolines via the functionalization of resin-bound tetrahydro-b-carboline derivatives is described. Reduction of the amide bonds and/or nitro group is the key step in the formation of different described fused heterocycles.