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Synthesis of new compounds containing the pyrazolo[3,4-b]pyridine-3-one subunit

✍ Scribed by S. Fadel; F. Suzenet; A. Hafid; E. M. Rakib; M. Khouili; M. D. Pujol; G. Guillaumet

Book ID: 102342022
Publisher: Journal of Heterocyclic Chemistry
Year: 2009
Tongue: English
Weight: 121 KB
Volume: 46
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.199

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✦ Synopsis

Abstract

magnified image A convenient route for the synthesis of pyrazolo[3,4‐b]pyridine‐3‐ones via condensation of 3‐amino‐1‐phenylpyrazolin‐5‐one with 4‐hydroxy‐6‐methylpyran‐2‐one is described. The pyrazolo[3,4‐b]pyridine‐3‐one isomers obtained were functionalized at 1‐, 4‐, or 6‐ position by different pharmacophore entities allowing the synthesis of new compounds with promising biological activities. J. Heterocyclic Chem., (2009).

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