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Synthesis of New Chiral Monodentate Phosphite Ligands and Their Use in Catalytic Asymmetric Hydrogenation

✍ Scribed by Hua, Zihao; Vassar, Victor C.; Ojima, Iwao


Book ID
127173260
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
69 KB
Volume
5
Category
Article
ISSN
1523-7060

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Synthesis of new chiral monodentate phos
✍ Kathrin Junge; Günther Oehme; Axel Monsees; Thomas Riermeier; Uwe Dingerdissen; 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 74 KB

A general synthesis of chiral 4,5-dihydro-3H-dinaphthophosphepines 1a-g is described. The resulting ligands represent a new class of monodentate chiral phosphines. First applications of 1a-g in the rhodium-catalyzed asymmetric hydrogenation of unsaturated carboxylic acid derivatives demonstrate the