Synthesis of new bis-3,5-diphenylpyrazolines derivatives linked with alkyl chains
✍ Scribed by Braulio Insuasty; Henry Martinez; Jairo Quiroga; Rodrigo Abonía; Manuel Nogueras; Justo Cobo
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2008
- Tongue
- English
- Weight
- 268 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
magnified image
New bis‐3,5‐diphenylpyrazoline derivatives have been synthesized according to Elway [1] (1999) and Sangwan's[2] (1992) methodology. Most of them were obtained in good yields, from the reaction between an alkyl linked bis‐chalcones and hydrazine in acetic acid. The activity of some bis‐pyrazolines was evaluated against Helicobacter pylori.
📜 SIMILAR VOLUMES
## Abstract Several 3,3′‐(1,4‐phenylene)bis(1,5‐diones) and their chalcone precursors have been prepared in good to excellent yield via aldol addition and Michael addition starting from 3‐acetyl‐2,5‐dimethylfuran or 3‐acetyl‐2,5‐dimethyl‐thiophene with terephthalaldehyde in the presence of appropri
## Abstract The preparation of novel alkyl monobridged 2,4‐dimethyl‐5‐amino‐benzo[__b__][1,8]naphthyiridine and benzo[__b__][1,8]naphthyridone derivatives by phase transfer catalysis is reported.