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Synthesis of New 4-Thiazolidinone-, Pyrazoline-, and Isatin-Based Conjugates with Promising Antitumor Activity

✍ Scribed by Havrylyuk, Dmytro; Zimenkovsky, Borys; Vasylenko, Olexandr; Gzella, Andrzej; Lesyk, Roman

Book ID
115470593
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
558 KB
Volume
55
Category
Article
ISSN
0022-2623

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## Abstract The synthesis and antitumor activity screening of novel isatin based conjugates with thiazolidine and pyrazoline moieties were performed. Reaction of 3,5‐diaryl‐4,5‐dihydropyrazoles with chloroacetyl chloride yielded starting 2‐chloro‐1‐(3,5‐diaryl‐4,5‐dihydropyrazol‐1‐yl)‐ethanones whi