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Synthesis of new 1H-imidazoles via reactions of 3(,5)-(di)chloro-2H-1,4-(benz)oxazin-2-ones with α-aminoketones

✍ Scribed by Bart P. Medaer; Georges J. Hoornaert


Book ID
108379290
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
940 KB
Volume
55
Category
Article
ISSN
0040-4020

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Synthesis of 3,5-dihalogeno-2H-1,4-oxazi
✍ L. Meerpoel; G. Hoornaert 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 199 KB

The title compounds 4 were obtained on treatment of qanohydrines 3 of aliphatic and aryl aldehydes with oxalyl chloride or bromide in chlorobenzene at 9&C. Evidence for their structure is given by their spectroscopic data and by the Diels Alder reaction of 4a and & with acetylenic dienaphiles to yie