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Synthesis of N-Substituted Indole-3-carboxylic Acid Derivatives via Cu(I)-Catalyzed Intramolecular Amination of Aryl Bromides

✍ Scribed by Melkonyan, Ferdinand S.; Karchava, Alexander V.; Yurovskaya, Marina A.


Book ID
115438471
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
183 KB
Volume
73
Category
Article
ISSN
0022-3263

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Synthesis of 1-Amino-1H-indole-3-carboxy
✍ Ferdinand Melkonyan; Artyom Topolyan; Marina Yurovskaya; Alexander Karchava 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 144 KB

## Abstract A simple route to various __N__‐substituted 1‐amino‐1__H__‐indole‐3‐carboxylates by use of copper(I)‐catalyzed intramolecular __N__‐arylation has been established. For the preparation of __N__‐monosubstituted and __N__‐unsubstituted derivatives, the cyclization of Boc‐protected enehydra