𝔖 Bobbio Scriptorium
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Synthesis of N-substituted 4-amino-2,3-pentamethylenequinolines

✍ Scribed by É. S. Abramochkin; M. E. Konshin


Book ID
112404820
Publisher
Springer
Year
1970
Tongue
English
Weight
196 KB
Volume
4
Category
Article
ISSN
0091-150X

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A robust, regioselective synthesis of 3-amino-1,2,4-triazoles is described. This reaction employs a key intermediate 2, which is coupled to carboxylic acids in good yields to afford intermediates 3a-d. These entities, in turn, react with a variety of hydrazines or hydrazine hydrochlorides to provide