Synthesis of N-[ring-G-3H]phenyllinoleamide and N-phenyl[1-14C]linoleamide as labelled standards for spanish toxic oil syndrome studies

An improved synthesis of labelled fatty

An improved synthesis of labelled fatty acid carboxamides. N -phenyl [9,10(n)-3H] oleamide and N -[ring-G-13C6] phenyloleamide as standards for spanish toxic oil syndrome studies

✍ Josefina Casas; Angel Messeguer 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 192 KB

## Abstract A one‐pot procedure for the high yield preparation of title compounds is reported. The key features involve the conversion of the fatty acid into the corresponding mixed anhydride by reaction with ethyl chloroformate, followed by reaction with aniline, using acetonitrile as solvent to e