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Synthesis of N, N-diethyl-4-[phenyl-(piperidin-4-ylidene)methyl]-[carboxy-14C]benzamide, a potent δ opioid receptor agonist

✍ Scribed by Lars Gawell

Book ID: 102373175
Publisher: John Wiley and Sons
Year: 2003
Tongue: French
Weight: 94 KB
Volume: 46
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.651

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✦ Synopsis

Abstract

The synthesis of carbon‐14 labelled N,N‐diethyl‐4‐[phenyl‐(piperidin‐4‐ylidene)methyl]‐benzamide is described. The radioisotope is introduced via an aryllithium reaction with ^14^CO~2~ to form the labelled acid, which is subsequently transformed into the amide. Copyright © 2002 John Wiley & Sons, Ltd.

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