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Synthesis of N-methylated cyclic peptides

✍ Scribed by Chatterjee, Jayanta ;Laufer, Burkhardt ;Kessler, Horst


Book ID
120981622
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
975 KB
Volume
7
Category
Article
ISSN
1750-2799

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## Abstract Systematic __N__‐methylation of all peptide bonds in the cyclic pentapeptide cyclo(‐D‐Ala‐Ala~4~‐) has been performed yielding 30 different __N__‐methylated derivatives, of which only seven displayed a single conformation on the NMR time scale. The conformation of these differentially _

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