Asymmetric synthesis of (S)-5 has been accomplished with an excellent enantiomeric excess by hydrogenation of raeemie 5 using ruthenium-BINAP-diamine-KOH system, followed by oxidation. Magnesium enolate of (2S)-2-methoxycyclohexanone [(S)-5] reacts with the 4-aeetoxyazetidinone 4 to give the key int
✦ LIBER ✦
Synthesis of N-ethoxycarbonyl-β-aminoketones —key intermediated for the preparation of nitrogen-containing heterocycles
✍ Scribed by N. V. Sivova; A. D. Shutalev
- Book ID
- 105103732
- Publisher
- Springer US
- Year
- 1995
- Tongue
- English
- Weight
- 109 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0009-3122
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