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Synthesis of N-[(6-diphenylmethylthio)-9-purinyl]acetylamino acids and N-(6-thio-9-purinyl)acetylamino acids

โœ Scribed by E. D. Kaverzneva; V. V. Kiseleva; L. I. Deeva


Book ID
112422618
Publisher
Springer
Year
1971
Tongue
English
Weight
389 KB
Volume
20
Category
Article
ISSN
1573-9171

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โœ H Mack; R Brossmer ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 224 KB

Aldol condensation of la with potassium di-tert-butyloxaloacetate yields the two epimeric 6-thiosialic acids 2 and 3. As opposed to this, reaction between thiofuranose 6 \_ and nickel (II)/oxaloacetate affords 6-thio-N-acetyl-D-neuraminic acid \_Ic. Substituting sulfur for oxygen in the pyranosering