## Abstract Nefopam hydrochloride (I), an analgesic agent, was labelled with carbon‐13 at C‐1,3,4 and 6 positions for metabolic studies. The starting materials for the synthesis included commercially available phthalic acid‐carboxyl‐^13^C~1~ (II) and 2‐methylaminoethyl‐1,2‐^13^C~2~ alcohol. The ext
Synthesis of N-(2, 5-[2-13C]dimethyl-1H-pyrrol-1-YL)-6-(4-morpholinyl)-3-Pyridazinamine hydrochloride
✍ Scribed by Nunzio Di Mola; Elvio Bellasio; Pietro Ferrari; Luigi F. Zerilli
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- French
- Weight
- 257 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The d e u t e r a t e d d i e n e was p r e p a r e d as r e p o r t e d by us [3]. from 1,2-dibromoethane-1 ,2-13C2 v i a t h e c y a n i d e , s u c c i n l c a c i d , bromosuccinic a c i d , fumaric a c i d and maleic a n h y d r i d e C4,51. The 13C-labelled maleic anhydride was p r e p a r e d
## Abstract __N__‐[1‐(4‐chlorophenyl)‐1H‐pyrrol‐2‐yl‐^13^C~4~‐methyleneamino]guanidinium acetate has been synthesized by a four‐step procedure. This involved reduction of the Weinreb amide __N__,__N′__‐dimethyl‐__N__,__N′__‐dimethyloxybutane‐1,4‐diamide‐1,2,3,4‐^13^C~4~ by Dibal‐H to give the corre