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Synthesis of Models of Metabolites: Oxidation of Variously Substituted Chromenes Including Acronycine, by a Porphyrin Catalytic System.

✍ Scribed by Bernardin Akagah; Francois Estour; Philippe Verite; Elisabeth Seguin; Francois Tillequin; Olivier Lafont

Publisher
John Wiley and Sons
Year
2006
Weight
24 KB
Volume
37
Category
Article
ISSN
0931-7597

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Synthesis of models of metabolites: Oxid
Synthesis of models of metabolites: Oxidation of variously substituted chromenes including acronycine, by a porphyrin catalytic system
✍ Bernardin Akagah; François Estour; Philippe Vérité; Elisabeth Seguin; Olivier La 📂 Article 📅 2005 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 124 KB

The influence of chemical neighbouring on oxidation of substituted 2,2-dimethylchromenes derivatives 5-8 by a biomimetic catalytic system was first studied. It was then applied to acronycine an anti-cancer drug in order to obtain in one single step oxidized products resulting from the reactivity of