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Synthesis of Methylated Resveratrol and Analogues by Heck Reactions in Organic and Aqueous Solvents.

✍ Scribed by Luis Botella; Carmen Najera


Publisher
John Wiley and Sons
Year
2004
Weight
24 KB
Volume
35
Category
Article
ISSN
0931-7597

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✍ Lutz F. Tietze; Wolf-RΓΌdiger Krahnert πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 296 KB

The stereoselective synthesis of structurally simplified heptacyclic cephalostatin analogues 2, 3, 18-21, 31, 32 and 33 by multiple Heck reactions is described. The key step of the synthesis is a selective Heck reaction of hydrindene 7 with 12 and 25, respectively at the vinyl bromide moiety followe