Synthesis of methyl ethers of methyl (methyl α-D-mannopyranosid)-uronate
✍ Scribed by E. V. Evtushenko; Yu. S. Ovodov
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 233 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0009-3130
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Methyl derivatives of methyl(methyl-a-D-glucopyranosid)uronate have been separated without derivatization as well as corresponding per-0-trimethylsilyl, trifluoroacetyl and per-0-acetyl derivatives on columns of different polarity. Good separation was obtained with both of the compounds bearing hydr
## Abstract Methyl 2‐__O__‐benzyl‐6‐deoxy‐3‐__C__‐methyl‐α‐D‐mannopyranoside (2) was synthesized in ten steps by starting from the readily available methyl 2,3‐anhydro‐4,6‐__O__‐benzylidene‐α‐D‐allo‐pyranoside (3). The key step was the stereoselective __cis__‐hydroxylation (cat. osmium(VIII) oxide)