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Synthesis of Marine Sponge Alkaloids Oroidin, Clathrodin, and Dispacamides. Preparation and Transformation of 2-Amino-4,5-dialkoxy-4,5-dihydroimidazolines from 2-Aminoimidazoles

โœ Scribed by Olofson, Anne; Yakushijin, Kenichi; Horne, David A.


Book ID
120267284
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
118 KB
Volume
63
Category
Article
ISSN
0022-3263

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A new synthesis of the 2-dimethylamino-4-hydroxy-6-methoxymethyl-3H-imidazo [4', 5' :3,4] pyfido[2,3-b]indole, used as key intermediate in the total synthesis of the alkaloids grossularines -1 and -2. based on the step-wise formation of the pyfidine and imidazole tings, is described.