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Synthesis of macromolecular Mitomycin C derivatives

โœ Scribed by Anne De Marre; Heidi Soyez; Etienne Schacht


Book ID
113275697
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
984 KB
Volume
32
Category
Article
ISSN
0168-3659

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Although adducts resulting from the reaction of mitomycin C (MC) and DNA have been characterized as guanine derivatives covalently linked to MC at the guanine N2-and/or 06-positions, lack of material and of protons on the guanine nucleus had led to difficulties in product characterization. Authentic