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Synthesis of Long-Chain Fatty Acid Enol Esters Isolated from an Environmental DNA Clone

✍ Scribed by Brady, Sean F.; Clardy, Jon


Book ID
118045909
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
146 KB
Volume
5
Category
Article
ISSN
1523-7060

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Several C27-C30 unsaturated fatty acids have been isolated from an Australian sponge, Amphimedon sp., as human DNA topoisomerasΒ’ I inhibitors. Three of them, amphimic acids A (1)-C (3), are unusual fatty acids possessing a cyclopropylidene group, and one is a new C30 fatty acid 4. Their structures