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Synthesis of L-α-aminoadipyl-L-serinyl-D-valine, a naturally occuring tripeptide from the fermentation of Penicillium chrysogenum

✍ Scribed by James E. Shields; Charles S. Campbell; K. Scott Doyle; Roger D. Miller; Norbert Neuss


Publisher
John Wiley and Sons
Year
1981
Tongue
German
Weight
283 KB
Volume
64
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

A new tripeptide, L‐α‐aminoadipyl‐L‐seryl‐D‐valine has been synthesized by coupling the protected L‐seryl‐D‐valine dipeptide with an appropriately protected L‐α‐aminoadipic acid ester. The free tripeptide was obtained after treatment with liquid HF and purification by HPLC.