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Synthesis of kifunensine, an immunomodulating substance isolated from microbial source

✍ Scribed by Hiroshi Kayakiri; Chiyoshi Kasahara; Teruo Oku; Masashi Hashimoto


Book ID
104226488
Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
126 KB
Volume
31
Category
Article
ISSN
0040-4039

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✦ Synopsis


A synthesis of kifunensinetl) has been achieved by a route involving, as a key step, a double cyclization of aldehyde 2 with ammonia.

. Polyhydroxylated piperidine and pyrrolidine alkaloids1 have attracted


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Asymmetric Synthesis of ES-285, an Antic
✍ Ana C. Allepuz; Ramón Badorrey; María D. Díaz-de-Villegas; José A. Gálvez 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 181 KB

## Abstract The asymmetric synthesis of (2__S__,3__R__)‐2‐amino‐3‐octanedecanol hydrochloride (ES‐285**·**HCl) was achieved in eight steps in ca. 38 % overall yield from the __N__‐benzylimine‐derived from (__R__)‐2,3‐__O__‐isopropylidene glyceraldehyde, which is easily available on gram scale from