Synthesis of ketene (S, Te)acetals and their transformation into Z-α-phenylthio-α,β-unsaturated aldehydes
✍ Scribed by Claudio C Silveira; Gelson Perin; Antonio L Braga; Miguel J Dabdoub; Raquel G Jacob
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 618 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
Aldehydes are converted into (E)-CI , fi -unsaturated carboxylic acids by means of C,O,O -tri(trimethylsilyl) ketene acetal and a catalytic amount of ZnBr2. Several ways have been described to transform aldehydes into c1 , 6 -unsaturated esters. However, the hydrolysis of the resultant esters to t
R\*,S\*) Selective aldol type reaction of O-methyl-C,O-bis(trimethylsilyl)ketene acetal (,j.) with aldehydes and stereoselective formation of c,B-unsaturated carboxylic esters are attained by the combination of 2-A and Lewis acids. One of the most versatile methods to E selective synthesis of a,$-un