Synthesis of ฮฑ-pyrones from ฮฑ-oxo ketene
โ
R.Karl Dieter; Jeffrey R. Fishpaugh
๐
Article
๐
1986
๐
Elsevier Science
๐
French
โ 235 KB
a-Ox0 ketene dithioacetals can be converted into a-pyrones in a three step process involving 1,2-nucleophilic addition of ester or ketone enolate anions, acid promoted rearrangement, and subsequent en01 lactonization. Utilization of ester enolates affords 6-alkylthio a-pyrones while ketone enolates