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Synthesis of isotopically labelled thiol volatiles and cysteine conjugates for quantification of Sauvignon Blanc wine

✍ Scribed by Katherine R. Hebditch; Laura Nicolau; Margaret A. Brimble


Publisher
John Wiley and Sons
Year
2007
Tongue
French
Weight
134 KB
Volume
50
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

The thiols 4‐mercapto‐4‐methylpentan‐2‐ol (4MMPOH), 3‐mercaptohexan‐1‐ol (3MH), and 3‐mercaptohexyl acetate (3MHA), which contribute to the aroma profile of Sauvignon Blanc, as well as other varieties of wine, have been synthesized with deuterium labels. The cysteinylated precursors of the thiols, 4‐(4‐methylpentan‐2‐one)‐L‐cysteine (4MMP‐cys) and 4‐(4‐methylpentan‐2‐ol)‐L‐cysteine (4MMPOH‐cys), found in grape must were also synthesized with deuterium labels. These deuterated compounds provide useful internal standards for the quantification of these thiols in wine using LCMS. Copyright © 2007 John Wiley & Sons, Ltd.