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Synthesis of isotopically labelled 3-amino-2-phenylpropionic acid and its role as a precursor in the biosynthesis of tenellin and tropic acid

โœ Scribed by Cox, Russell J.; O'Hagan, David


Book ID
111686918
Publisher
Royal Society of Chemistry
Year
1991
Weight
527 KB
Volume
10
Category
Article
ISSN
1472-7781

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โœ William J. Wheeler; Douglas D. O'Bannon; Joseph H. Kennedy; James A. Monn; Roger ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 177 KB

As part of a program aimed at the design of conformationally constrained analogs of glutamic acid, (+)-2-aminobicyclo[3.1.0]hexane-2,6-carboxylic acid (1), identified as a highly potent, selective, group II metabotropic glutamate receptor agonist has been synthesized and studied clinically. Heterocy