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Synthesis of Isoquinolines and Pyridines by the Palladium-Catalyzed Iminoannulation of Internal Alkynes

✍ Scribed by Roesch, Kevin R.; Zhang, Haiming; Larock, Richard C.


Book ID
124049583
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
124 KB
Volume
66
Category
Article
ISSN
0022-3263

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Synthesis of isoquinolines and pyridines
✍ Jeroen J.H. Diederen; Rene W. Sinkeldam; Hans-W. FrΓΌhauf; Henk Hiemstra; Kees Vr πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 203 KB

Various isoquinolines and pyridines were prepared from aryl-and vinyl halides by a method which involves insertion of an allene into the Pd-C bond and intramolecular nucleophilic attack of the imine.