Synthesis of Isoquinoline Derivatives via Ag- Catalyzed Cyclization of 2-Alkynyl Benzyl Azides
β Scribed by Niu, Yan-Ning; Yan, Ze-Yi; Gao, Guo-Lin; Wang, Hong-Li; Shu, Xing-Zhong; Ji, Ke-Gong; Liang, Yong-Min
- Book ID
- 118157930
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 194 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
Intramolecular cyclization of 2-alkynyl benzyl azides in the presence of AuCl 3 and AgSbF 6 in THF under a pressured vial at 100 Β°C gives the corresponding isoquinolines in good yields. Similarly, the five-membered analogs afford the corresponding isoquinolines.
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