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Synthesis of isogranulatimide analogues possessing a pyrrole moiety instead of an imidazole heterocycle

โœ Scribed by Bernadette Hugon; Bruno Pfeiffer; Pierre Renard; Michelle Prudhomme

Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
224 KB
Volume
44
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

An efficient four step synthesis from commercial indoles of isogranulatimide analogues is reported. In the new compounds, the imidazole moiety is replaced by a pyrrole unit, the indole part is substituted or not in 5-position and the nitrogen of the imide moiety bears or not a methyl substituent.

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