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Synthesis of Internal Alkynes through the Pd-Catalyzed Coupling of Heteroaryl Halides with Terminal Alkynes

✍ Scribed by Lu, Linhua; Yan, Hong; Sun, Peng; Zhu, Yan; Yang, Hailong; Liu, Defu; Rong, Guangwei; Mao, Jincheng


Book ID
120008769
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
530 KB
Volume
2013
Category
Article
ISSN
1434-193X

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Coupling reaction of aryl and vinyl halides with terminal alkynes using a catalyst system of copper(I) iodide -triphenylphosphine proceeds efficiently in the presence of potassium carbonate to give the corresponding unsymmetrical acetylenes in good yield.