Synthesis of interleukin-1β in primary biliary cirrhosis: Relationship to treatment with methotrexate or colchicine and disease progression*1

Synthesis of interleukin-1β in primary b

Synthesis of interleukin-1β in primary biliary cirrhosis: Relationship to treatment with methotrexate or colchicine and disease progression

✍ Laurie C. Miller; Dr Archna Sharma; Augusta F. McKusick; Dr Joseph P. Tassoni; C 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 702 KB

Primary biliary cirrhosis (PBC) is a chronic, progressive, cholestatic liver disease. Interleukin-lp (JL-lp) may play a role in the pathogenesis of PBC by contributing to altered immune function and fibrosis. Colchicine or methotrexate has some beneficial effects in the treatment of PBC, and also af