Synthesis of indolizidine and pyrrolizidine alkaloids by the [2+2] cycloaddition of endocyclic enecarbamates to alkyl ketenes
β Scribed by Carlos Roque D. Correia; Antonio R. de Faria; Eliane S. Carvalho
- Book ID
- 103401461
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 235 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
The diastereofacial selectivity of enecarbamates bearing a chiral auxiliary was evaluated for the [2+2]cycloaddition with dichloroketenes. Diastereofacial selectivity ranged from zero (bornyl and menthyl) to 60% (Greene's auxiliary and 8-phenylmenthyl). Chromatography separation of the diastereomeri
Novel aza-bicyclic 2-isoxazolines, 4,5-dihydroisoxazole [5,4-b]pyrrolidines, and 4,5-dihydroisoxazole[5,4b]piperidines were synthesized in a highly regioselective manner through a 1,3-dipolar cycloaddition reaction of 5-and 6-membered endocyclic enecarbamates and enamides with several nitrile oxides