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Synthesis of Indolines via Pd(II)-Catalyzed Amination of C–H Bonds Using PhI(OAc) 2 as the Bystanding Oxidant

✍ Scribed by Mei, Tian-Sheng; Leow, Dasheng; Xiao, Han; Laforteza, Brian N.; Yu, Jin-Quan


Book ID
120373905
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
281 KB
Volume
15
Category
Article
ISSN
1523-7060

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A chelation-assisted palladium-catalyzed acyloxylation of the sp 3 C-H bond of benzyl by carboxylic acid is described, which employs PhI(OAc) 2 as a stoichiometric oxidant. The procedure tolerates a series of functional groups, such as methoxyl, chloro, bromo, iodo, vinyl, formyl, phenolic hydroxyl,