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Synthesis of indole-3-carboxamides via a haloform cleavage reaction of 3-trifluoroacetylindole with lithium dialkylamides

✍ Scribed by Heidi L. Hassinger; Richard M. Soll; Gordon W. Gribble

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
223 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

Reaction of 3-trifluoroacetylindole (4) with lithium dialkylamides affords the corresponding indole-3-carboxamides (5) in good to excellent yields.

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