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Synthesis of Imidazo[1,2- a ]pyridine C-Nucleosides with an Unexpected Site of Ribosylation
β Scribed by Gudmundsson, Kristjan S.; Drach, John C.; Townsend, Leroy B.
- Book ID
- 120369907
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 293 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
carbon-carbon bonds for the synthesis of new C-nucleoside analogs 7 and 8. These two isomers, possessing altered positions of nitrogen and oxygen atoms, can be formed through dipolar cycloaddition reactions of the appropriate olefms and nitrile oxides.
Synthesis of Novel Isoxazolinyl Substituted Imidazo[1,2-a]pyridine C-Nucleoside Analogues. -The title isomeric C-nucleoside analogues (VI) and (IX) having hydroxymethyl-substituted isoxazoline rings in place of the ribose ring are prepared by a strategy involving cycloaddition of olefins to interme