Synthesis of hydroxy- and methoxy-substituted octahydrobenzo[g]isoquinolines as potential ligands for serotonin receptors

Synthesis, labelling and evaluation of h

Synthesis, labelling and evaluation of hydantoin-substituted indole carboxylic acids as potential ligands for positron emission tomography imaging of the glycine binding site of the N-methyl-d-aspartate receptor

✍ A. Bauman; M. Piel; S. Höhnemann; A. Krauss; M. Jansen; C. Solbach; G. Dannhardt 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 1009 KB

The __N__‐methyl‐ d‐aspartate (NMDA) receptor as a type of ionotropic glutamatergic receptors is essential for physiological processes such as learning, memory and synaptic plasticity. A glutamate‐induced overactivation of these receptors, accompanied by increased intracellular calcium concentration