Synthesis of hydrolytic enzymes during production of tylosin byStreptomyces fradiae

Metabolic adaptation of Escherichia coli

Metabolic adaptation of Escherichia coli during temperature-induced recombinant protein production: 1. Readjustment of metabolic enzyme synthesis

✍ Frank Hoffmann; Jan Weber; Ursula Rinas 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 249 KB 👁 2 views

## Abstract The metabolic burden and the stress load resulting from temperature‐induced production of human basic fibroblast growth factor is connected to an increase in the respiratory activity of recombinant __Escherichia coli__, thereby reducing the biomass yield. To study the underlying changes