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Synthesis of hydantoins transformable to 3-alkylorotic acids from aminofumarate and isocyanates

✍ Scribed by Stephen S. Washburne; Kwanghee K. Park


Book ID
112123420
Publisher
Journal of Heterocyclic Chemistry
Year
1975
Tongue
English
Weight
177 KB
Volume
12
Category
Article
ISSN
0022-152X

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## Abstract A series of new optically active 1__H__‐imidazole 3‐oxides **5** with a substituted acetate group at N(1) as the chiral unit were prepared by the reaction of __Ξ±__‐(hydroxyimino) ketones, __Ξ±__‐amino acid methyl esters, and formaldehyde. In an analogous reaction, ethyl 2‐(hydroxyimino)‐