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Synthesis of Hyaluronic Acid Oligomers using Chemoselective and One-Pot Strategies

✍ Scribed by Dinkelaar, Jasper; Gold, Henrik; Overkleeft, Herman S.; Codée, Jeroen D. C.; van der Marel, Gijsbert A.


Book ID
127083898
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
278 KB
Volume
74
Category
Article
ISSN
0022-3263

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Multi-Gram Synthesis of a Hyaluronic Aci
✍ Mickaël Virlouvet; Michael Gartner; Katarzyna Koroniak; Jonathan P. Sleeman; Ste 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 234 KB

## Abstract Fully protected tetra‐, hexa‐ and octasaccharides of hyaluronic acid were synthesized on a scale of several 100 mg up to gram quantities using allyl (methyl 2‐__O__‐benzoyl‐3‐__O__‐benzyl‐4‐__O__‐levulinoyl‐__β__‐D‐glucopyranosyluronate)‐(1→3)‐4‐__O__‐acetyl‐6‐__O__‐benzyl‐2‐deoxy‐2‐tri