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Synthesis of histidine2-angiotensin II analogues

โœ Scribed by P. Cordopatis; D. Theodoropoulos


Book ID
112657811
Publisher
Springer
Year
1975
Tongue
English
Weight
194 KB
Volume
31
Category
Article
ISSN
1420-682X

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Conformational analysis of cyclic angiot
โœ Juris Balodis; Alexander Golbraikh ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer Netherlands ๐ŸŒ English โš– 298 KB

Conformationally restricted cyclic analogues of angiotensin II (ANG II), Aspl-Arg2-ValLTyr4-ValS-His6-Pro 7-Phe 8, with a link between positions 3 and 5 have considerable biological activity. It is proposed that the spatial arrangement of the pharmacophore groups of Tyr a, His 6 and Phe 8 side chain