Synthesis of highly potent RXR-specific retinoids: The use of a cyclopropyl group as a double bond isostere
β Scribed by Vidyasagar Vuligonda; Yuan Lin; Roshantha A.S. Chandraratna
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 298 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0960-894X
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## Intramolecular cyclization of trisilanyl ethers of homoallylalcohols proceeded regio-and stereoselectively with a 5-exo mode to give 3-(disilanylmethyl)-24latetrahydrofuran derivatives in good yields in the presence of a t-alkyl isonitrile-palladium catalyst. From the cyclized products thus obt