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Synthesis of Highly Functionalized Isoxazolinediones from One-pot Reaction of AlkylideneMeldrum’s Acid with Alkyl Isocyanides in the Presence of Arylhydroxylamines

✍ Scribed by Azizollah Habibi; Leyla Mousavifar; Issa Yavari; Mohammad R. Yazdanbakhsh


Book ID
106213847
Publisher
Springer Vienna
Year
2007
Tongue
English
Weight
167 KB
Volume
138
Category
Article
ISSN
0026-9247

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Reaction between alkyl isocyanides and d
✍ Issa Yavari; Abdolali Alizadeh; Mohammad Anary-Abbasinejad; Hamid R Bijanzadeh 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 105 KB

Protonation of the highly reactive 1:1 intermediates produced in the reaction between alkyl isocyanides and dibenzoylacetylene by saccharin, phthalimide, or 4-methyl-5-nitroimidazole, leads to vinylnitrilium cations, which undergo carbon-centered Michael type addition with the conjugate base of the