Synthesis of highly enantiomerically enriched N-Boc-α-amino ketones from pseudoephedrine N-Boc-α-amino acid amides
✍ Scribed by Andrew G. Myers; Taeyoung Yoon
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 234 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
N-(α-Stannylalkyl) oxazolidinones can be obtained as a mixture of diastereomers in three steps from aldehydes with yields dependent on the R group of R-CHO. They can be transformed by a tin-lithium exchange to N-(α-lithioalkyl)oxazolidinones which equilibrate rapidly to one diastereomer. These comp