Poly(L-lactic acid) (PLLA) was produced by the melt polycondensation of L-lactic acid. For the optimization of the reaction conditions, various catalyst systems were examined at different temperature and reaction times. It was discovered that Sn(II) catalysts activated by various proton acids can pr
Synthesis of High-Molecular-Weight Poly(L-lactic acid) by Direct Polycondensation
β Scribed by Ki Woong Kim; Seong Ihl Woo
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 212 KB
- Volume
- 203
- Category
- Article
- ISSN
- 1022-1352
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## Abstract Starting from D,Lβacid and SnCl~2~ as catalyst, poly(D,Lβlactic acid) (PDLLA) was directly synthesized by melt polycondensation. Under the appropriate conditions such as 0.5 wt % SnCl~2~, 170β180Β°C, 70 Pa, and 10 h, the viscosityβaverage molecular weight (__M__~Ξ·~) of PDLLA was 4100 Da.
## Abstract Poly(glutamic acidβ__co__βlactic acidβ__co__βglycolic acid) (PGLG), an amphiphilic biodegradable copolymer, was synthesized by simply heating a mixture of Lβglutamic acid (Glu), DLβlactic acid, and glycolic acid with the present of stannous chloride. The unique branched architecture com