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Synthesis of haptens for the development of a solid-phase immobilized epitope-immunoassay (SPIE-IA) of AZT-TP

✍ Scribed by Luc Lebeau; Thierry Brossette; Laure Goujon; Christophe Créminon; Jacques Grassi; Charles Mioskowski

Book ID: 104261568
Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 238 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(99)00785-6

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✦ Synopsis

The synthesis of the reduced form of AZT-triphosphate, Y-amino-Y-deoxythymidine-5'-triphosphate, and of its stable analog, 3'-amino-3'-deoxythymidine-5'-(~:~,~bis-methylene)triphosphate, is described. AMT-TP and AMT-PCPCP were prepared to develop a specific immunometric assay for AZT-TP.

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